Penn Medicine station is a train station in the University City section of Philadelphia, Pennsylvania on the SEPTA Regional Rail system. The station serves the area around the University of Pennsylvania, and is located at South Street and Convention Avenue. Located on the West Chester Branch, it serves the Airport, Wilmington/Newark, Media/Wawa, Manayunk/Norristown, Warminster, and West Trenton Regional Rail services. In 2013, this station saw 3,091 boardings and 2,950 alightings on an average weekday.